The Search Continues

Government Shutdown

Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted.

The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit

Updates regarding government operating status and resumption of normal operations can be found at

There is still a lot that scientists don’t know about the effects of opioids on the brain. Maybe someday you will make the next big discovery!

Until then, join me—Sara Bellum—in the magazines in my series, as we explore how drugs affect the brain and nervous system.

Mind Over Matter is produced by the National Institute on Drug Abuse, National Institutes of Health, U.S. Department of Health and Human Services. These materials are in the public domain and may be reproduced without permission. Citation of the source is appreciated. NIH Publication No. 14-3856. Printed 1997. Reprinted 1998, 2000, 2003, 2005, 2006, 2007. Revised 2009, 2014.

This publication is available for your use and may be reproduced in its entirety without permission from NIDA. Citation of the source is appreciated, using the following language: Source: National Institute on Drug Abuse; National Institutes of Health; U.S. Department of Health and Human Services.