Spice has only been around a few years, and research is only just beginning to measure how it affects the brain. What is known is that the chemicals found in Spice attach to the same nerve cell receptors as THC, the main mind-altering ingredient in marijuana. Some of the chemicals in Spice, however, attach to those receptors more strongly than THC, which could lead to much stronger effects. The resulting health effects can be unpredictable and dangerous. Additionally, there are many chemicals that remain unidentified in products sold as Spice and it is therefore not clear how they may affect the user. It is important to remember that chemicals are often being changed as the makers of Spice often alter them to avoid drug laws, which have to target certain chemicals.
Learn more about how the brain works and what happens when a person uses drugs.