Prescription Pain Medications (Opioids) Blog Posts

Pain killers are dangerous to your health. Learn more about the health effects of using ′Vicodin′ and  ′Oxycontin′ (oxy) and explore the data on teen opioid usage.

English Common Street Names
Oxy, Percs, Vikes
Related Translated TID

Mind Matters: The Body's Response to Opioids

Hi there! Mind Matters (formerly referred to as Mind Over Matter) is a series that explores the ways that different drugs affect your brain, body, and life. In this issue we are going to talk about opioids.

View the Mind Matters Teacher's Guide.

Ways opioid medicines are misused:

  • not following the instructions from your doctor
  • taking pills that are not prescribed for you
  • taking opioids to get high

You may have been hearing a lot about opioids lately. It’s possible you know them as drugs called oxy or Vikes.

Opioids have been used for thousands of years. Some opioids come from plants. Others are made in a lab.

Prescription opioids are used as medicine but can also be misused. Illegal opioids are only used to get high. Misusing prescription opioids or taking any illegal opioid can be dangerous.

What are opioids?


Girl holding a pill bottle in front of a medicine cabinet.
  • Doctors prescribe opioids to people who are in serious pain from things like dental surgery, sports injuries, and cancer.
  • If people follow their doctor’s instructions and take the right amount of medicine, opioids can help their pain go away.
  • But these medicines can also be dangerous if misused.

Examples of opioid pills are OxyContin®, Percocet®, and Vicodin®. People sometimes call opioid medicines different names like Happy Pills, Hillbilly Heroin, OC, Oxy, Percs, or Vikes.

Heroin and Fentanyl

  • Heroin is an illegal opioid that people use to get high, often with a needle.
  • It can be a white or brown powder, or a black sticky substance called black tar heroin.
  • Sometimes people call heroin names like big H, horse, brown sugar, hell dust, and smack.
  • Another illegal opiod is fentanyl, a white powder many times more powerful than heroin. 
  • Sometimes street heroin is laced (mixed) with fentanyl and this causes many overdoses. 

Both opioid medicine and illegal opioids like heroin and fentanyl can cause addiction, overdose, or even death. 

Learn more on our Drug Facts page: How many teens misuse prescription drugs?

How do opioids work?

Drawing of how opioids attach to receptors in the brain to block pain.

Opioids affect nerve cells (neurons) in your brain and body. They tell your brain to block pain and they also make you feel calm and happy.

What are opioids' effects?

Short-Term Effects

  • Feelings of calm, sleepiness, confusion
  • Slowed or stopped breathing (can cause fatal overdose)
  • Nausea, vomiting
  • Constipation

Long-Term Effects

  • Addiction
  • Heart infection
  • Lung infection
  • Muscle pain

Learn more: See our latest updates on opioids and prescription drugs.

How do you become addicted to opioids?

More people in the U.S. die from opioid overdoses than from other drugs.

Over time, the body gets used to having the drug and feels terrible without it. Withdrawl is like having the flu but much worse, and it can make it hard to stop taking the drug. If a person starts seeking and taking an opioid despite how it is interfering with work, school, or relationships, it is called addiction.

It’s important to know that anyone can become addicted to opioids. It doesn’t matter where you live or how smart you are. There is no way to predict who is likely to become addicted.

Learn more: What questions do teens ask about opioids and prescription drugs?

How do opioids affect your life?

When you're on opioids, the things that used to make you happy become impossible to enjoy.

If you are addicted to opioids, the drug can take over your life. Getting more opioids and getting high can become all you think about. And it makes it hard for you to enjoy things that used to make you happy.

Can you imagine if the things you loved no longer made you feel happy?

What if someone I know needs help?

If you think a friend or family member has a problem with drugs, talk to an adult you trust - like a parent, coach, or teacher - right away. Remember, treatment is available and people can get better.

Download PDF
Drugs and the Teen Brain

This lesson, provides scientific information about teen brain development and the effect of drugs and alcohol use on the brain.

A Dangerous Mix

In this lesson, students will get an understanding of the unexpected and potential dangerous effects associated with mixing medications and...

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Content on this site is available for your use and may be reproduced in its entirety without permission from NIDA. Citation of the source is appreciated, using the following language: Source: National Institute on Drug Abuse; National Institutes of Health; U.S. Department of Health and Human Services.