Street names: Blow, Coke, Crack

What is cocaine?

Also known as: Coke, Coca, C, Snow, Flake, Blow, Bump, Candy, Charlie, Rock, and Toot

A pile of cocaine

Cocaine is an addictive stimulant drug made from the leaves of the coca plant native to South America. Cocaine comes in two forms:

  • Powder cocaine is a white powder (which scientists call a hydrochloride salt). Street dealers often mix cocaine with other substances like cornstarch, talcum powder, or sugar. They also mix cocaine with active drugs like procaine, a local anesthetic (a chemical that causes you not to feel pain in a specific area of the body), and with other stimulants like amphetamines.
  • Crack is a form of cocaine that has been processed to make a rock crystal that people smoke. The term “crack” refers to the cracking sound the rocks make when they are heated. To make crack, the powder cocaine is mixed with ammonia or baking soda and water and then heated to produce the crystal.

How is cocaine used?

Powder cocaine can be snorted up the nose or mixed with water and injected with a needle. Sometimes, powder cocaine is rubbed onto gums or other tissues in the body. Crack is smoked in a small glass pipe. The crystal is heated to produce vapors that are absorbed into the blood through the lungs.

In order to keep the “high” going, people may take the drug repeatedly within a short period of time, at increasingly higher doses.

How does cocaine affect the brain?

All drugs change the way the brain works by changing the way nerve cells communicate. Nerve cells, called neurons, send messages to each other by releasing chemicals called neurotransmitters. These neurotransmitters attach to molecules on neurons called receptors. (Learn more about how neurotransmitters work.) Drugs affect this signaling process.

There are many neurotransmitters, but dopamine is the main one that makes people feel good when they do something they enjoy, like eating a piece of chocolate cake or playing a video game. Normally, dopamine gets recycled back into the cell that released it, thus shutting off the signal. Stimulants like cocaine prevents the dopamine from being recycled, causing a buildup of the neurotransmitter in the brain. It is this flood of dopamine that causes cocaine’s high. The drug can cause a feeling of intense pleasure and increased energy.

With repeated use, stimulants like cocaine can disrupt how the brain’s dopamine system works, reducing a person’s ability to feel  pleasure from normal, everyday activities.  People will often develop tolerance, which means they must take more of the drug to get the desired effect.  If a person becomes addicted, they may take the drug just to feel “normal.”

After the "high" of the cocaine wears off, many users experience a "crash" and feel tired or sad for days. They also experience a strong craving to take cocaine again to try to feel better.

Learn more about  how the brain works and what happens when a person uses drugs. And, check out how the brain responds to natural rewards and to drugs.

What are the other effects of cocaine?

The surge of dopamine in the brain affects the body in a variety of ways:

  • constricted blood vessels and dilated pupils
  • higher body temperature
  • higher blood pressure and faster heartbeat
  • feeling sick to the stomach
  • restlessness
  • decreased appetite and, over time, a loss of weight
  • inability to sleep
  • increased risk of heart attack or stroke due to high blood pressure
  • increased risk of HIV because of impaired judgment leading to risky sexual behavior
  • strange, unpredictable behavior, panic attacks, or paranoid psychosis (losing touch with reality)

How cocaine is used leads to different physical problems, including:

  • snorting: hoarse voice, loss of the sense of smell, nosebleeds, and a constant runny nose
  • taken by mouth: reduced blood flow in your intestines, leading to bowel problems
  • needle injection: higher risk of getting HIV, hepatitis C (a liver disease), and other diseases transmitted by blood contact

Can you get addicted to cocaine?

Yes, repeated cocaine use can lead to addiction. Addiction is a devastating brain disease in which people can’t stop using drugs even when they really want to and even after it causes terrible consequences to their health and other parts of their lives.

Because a cocaine high usually doesn't last very long, people take it again and again to try to keep feeling good. Once addicted, people who are trying to quit taking cocaine might experience withdrawal symptoms, including:

  • depression
  • feeling very tired
  • increased appetite
  • bad dreams and trouble sleeping
  • slowed thinking

The right treatment, however, can help an addicted person control their cravings and stop using cocaine.

Can you die if you use cocaine?

Yes. In 2014, more than 5,400 people died from a cocaine overdose. Males are much more likely to die in this way than are females. In 2014, 3,900 males overdosed on cocaine, as compared with 1,500 females.1

Cocaine can be deadly when taken in large doses or when mixed with other drugs or alcohol. Cocaine-related deaths often happen because the heart stops (cardiac arrest), then breathing stops. Using cocaine and drinking alcohol or using other drugs increases these dangers, including the risk of overdose. For example, combining cocaine and heroin (known as a “speedball”) puts a person at higher risk of death from an overdose.

In rare instances, sudden death can occur on the first use of cocaine or soon after.

1Centers for Disease Control and Prevention, National Center for Health Statistics. Underlying Cause of Death 1999-2014 on CDC WONDER Online Database, released 2015. Available at

How many teens use cocaine?

For the most recent statistics on cocaine use among teens, see the results below from NIDA’s Monitoring the Future study.

Swipe left or right to scroll.

Monitoring the Future Study: Trends in Prevalence of Various Drugs for 8th Graders, 10th Graders, and 12th Graders; 2015 (in percent)*


Time Period

8th Graders

10th Graders

12th Graders







Past Year





Past Month




Crack Cocaine






Past Year





Past Month




* Data in brackets indicate statistically significant change from the previous year.

Source: University of Michigan, Monitoring the Future Study

For more statistics on teen drug use, see NIDA’s Monitoring the Future study.

What should I do if someone I know needs help?

If you, or a friend, are in crisis and need to speak with someone now, please call:

  • National Suicide Prevention Lifeline at 1-800-273-TALK (they don't just talk about suicide—they cover a lot of issues and will help put you in touch with someone close by).

If you need information on treatment and where you can find it, you can call:

For more information on how to help a friend or loved one, visit our Have a Drug Problem, Need Help? page.

For More Information on Cocaine

Drug Facts



Statistics and Trends


Centers for Disease Control and Prevention

Monitoring the Future (University of Michigan):

Substance Abuse and Mental Health Services Administration:

Blog Posts

Chat Day Transcripts


See below for text description

Drug and Alcohol Use in College-Age Adults in 2014

Published: December 21, 2015
The 2014 Monitoring the Future College Students and Adults survey shows trends in alcohol, marijuana, nicotine, and stimulant use in college students and non-college peers.
See text description below

Monitoring the Future 2015 Survey Results

Published: December 16, 2015
NIH’s 2015 Monitoring the Future survey shows long term decline in illicit drug use, prescription opioid abuse, cigarette and alcohol use among the nation’s youth.
Dirty Money and Cocaine

Dirty Money and Cocaine

Published: December 18, 2014
Dirty money: find out just how much of your cash may be soiled with cocaine and bacteria.