NIDA for Teens: The Science Behind Drug Abuse
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Stimulants

The Buzz on Caffeine

Do your parents or teachers start the day with a cup of coffee? There’s no question that coffee is a popular drink—the National Coffee Association estimates that Americans drink 400 million cups of coffee a day. It’s the caffeine in coffee that provides the energy boost that many people claim they need to function. Caffeine has that perk-up effect because it is a stimulant. It blocks a brain chemical, adenosine, which causes sleepiness. Caffeine is found in tea leaves, coffee beans, cacao (used to make chocolate), and cola nuts (which come from the plant that gives soda its flavor). Caffeine is also found in many foods and drinks—non-cola sodas like root beer and orange soda, hot cocoa, and ice cream—and some medicines. The latest place to find caffeine is in energy drinks. Caffeine’s Effects—Not Totally Harmless Caffeine is a mild stimulant and not a drug, so its use isn’t regulated like prescription drug use is. Still, consuming too much caffeine can make you feel jittery or jumpy—your heart may race and your palms may sweat. If caffeine is taken in combination with other substances, like alcohol, it can really be dangerous because mixing a stimulant and a depressant like alcohol confuses the brain. A recent report from the Substance Abuse and Mental Health Services Administration shows that emergency room visits for high doses of caffeine have increased sharply. The likely cause is caffeine-infused energy drinks mixed with alcohol. Those most affected? Young people between 18 and 25 years old. So What’s a Body To Do? Everyone needs to perk up in the middle of a long day from time to time, but a jolt of caffeine isn’t your only option. Here are a few alternatives you can try to feel energized without overdoing the caffeine:
  • Sleep. This may sound obvious, but getting enough sleep is important. Teens need 9 hours of sleep a night.
  • Eat regularly. When you don’t eat, your glucose (sugar) levels drop, making you feel drained. Some people find it helpful to eat four or five smaller meals throughout the day instead of fewer big meals.
  • Drink enough water. Since we are more than two-thirds H20, our bodies need at least 64 ounces of water a day.
  • Take a walk. If you’re feeling drained in the middle of the day, it helps to move around. Do sit-ups or jumping jacks. Go outside for a brisk walk, ride your bike.
Now we want to know: What strategies help you keep your energy up during the day? Cup of coffee with coffee beans

Take a Breath of Fresh...Energy?

Sound too good to be true? Well, it is, and it may not be too good for you, either.

AeroShot is a dry caffeine “shot.” Each AeroShot has a powder blend of candy-flavored caffeine and B vitamins that you suck into your mouth and then swallow. Each canister has as much caffeine as a cup of coffee, but only takes six “inhales” to consume.

Questionable Marketing Claims

Breathable Foods started out marketing AeroShot as “breathable energy” in a “caffeine inhaler,” despite its being a powder. In response, the Food and Drug Administration (FDA) investigated AeroShot and issued a warning letter for false and mislabeled packaging, since it’s a powder that you swallow.

Although AeroShot has corrected its labeling, its false advertising only shows how important it is to know the facts about products before you consume them. AeroShot’s claims that its caffeine “shots” were breathable were simply untrue—and potentially dangerous.

Unknown Health Effects

The health effects of AeroShot are still unclear.

One worry is that AeroShot makes it too easy for users, especially youth, to over-do caffeine. Drinking a cup of coffee takes many sips over time, but “puffing” multiple AeroShots can give you an alarming amount of caffeine in a couple of minutes. Caffeine is a chemical stimulant that affects the brain and body—and too much can result in overdose.

FDA was also concerned that the original advertisements of AeroShot showed young people using the product with alcohol. Having already heard about Four LOKO and mixing energy drinks with alcohol, you know by now that it’s dangerous to mix caffeine (a stimulant) and alcohol (a depressant), because they confuse the body by sending opposite chemical signals to the brain. Caffeine can reduce people’s ability to feel how drunk they really are and therefore cause them to drink more than they normally would.

What do you think? How can AeroShot market itself in a way that does not encourage dangerous behavior?

Check out our post, The Buzz on Caffeine, for alternative ways to boost your energy.

Lightning bolt logo.

Prescription Stimulants Affect People With ADHD Differently

There’ve been lots of headlines lately about the dangers of prescription drug abuse—like taking a friend’s.

From this positron emission tomography (PET) scan, you can see how natural dopamine levels are different in people with and without ADHD. The scan on the left shows the brain of someone without ADHD, and the scan on the right shows the brain of someone with ADHD. The greater concentration of yellow, orange, and red in the nucleus accumbens in the scan on the left reflects a higher amount of dopamine.

BUT—for people who do not have ADHD, stimulants flood the brain with dopamine, causing a dopamine overload. So instead of having a calming effect as they would on people with ADHD, stimulants taken without a medical reason can disrupt brain communication and cause euphoria. It might feel good at first, but repeated abuse of stimulants can:

  • Increase blood pressure, heart rate, and body temperature.
  • Decrease appetite and sleep.
  • Cause feelings of hostility and paranoia.
  • Increase a person’s risk for addiction.

Doctors take many factors into account when prescribing a drug for a person who needs it: dose size, the person’s weight and height, how long the drug should be taken, and much more. The bottom line is that drugs affect everyone differently. Want to see how abusing Adderall could affect you physically and academically? Choose Your Path.

Virtual Brain Training

Imagine you are a teen with ADHD. It’s hard for you to focus in class, your mind wanders everywhere, and even though you want to do well in class you’d much rather be outside shooting hoops. Although you take notes, it’s hard for you to remember the teacher’s instructions. So after a medical evaluation, your doctor prescribes stimulants to help you focus. That’s what happened to NIDA’s second place Addiction Science Award winner, Kevin Knight, a 17-year-old junior at Collegiate High School in Niceville, Florida. Based on his own experience, Kevin wanted to know if there were other ways besides medication to train his brain to focus.

So he decided to take a scientific look at computer programs designed to improve focus and memory with his project, "Improving ADHD Treatment: A Comparison of Stimulant Medication Treatment for Children with ADHD."

Computerized Cognitive Training of Attention and Working Memory, and the Combination of the Two," took a lot of work (even more than coming up with that title!) He worked with doctors to find teenage volunteers with ADHD to see if they could improve their focus and memory by playing computer “brain games.”

Kevin was surprised by what he learned. The best outcomes came with kids who took their medication AND used the computer programs. They had better focus and better memory. Kevin even tested himself, and improved his own ability to focus. This suggests that computer games used with medications could be part of an effective approach for treating ADHD.

Why was this given an “Addiction Science” award? Because the medications prescribed for ADHD, such as Ritalin and Adderall, are stimulants, and stimulants can be abused. Some kids even give or sell the pills to their friends, which can be dangerous. For more information on stimulants taken for ADHD, check out http://www.nida.nih.gov/infofacts/ADHD.html.

NIDA’s Addiction Science award is given at the annual Intel International Science and Engineering Fair (ISEF), which was in San Jose this year. For more information on NIDA’s 3 winners, see NIDA’s news release at http://www.nida.nih.gov/newsroom/10/NR5-14.html

What is part of your personal experience that might be the basis of a cool science fair project?

Four people at a science fair.

Bath Salts: An Emerging Danger

Bath salts—the drug, not the perfumed crystals you put in bath water—showed up just a few years ago. The synthetic powder is sold online and in drug paraphernalia stores under a variety of names, such as "Blue Silk," "Zoom," "Cloud Nine," and "Hurricane Charlie." But don’t let the fun names fool you: Bath salts are extremely dangerous.

What Are Bath Salts?

Bath salts are a new family of drugs that contain synthetic chemicals related to cathinone, an amphetamine-like stimulant. Bath salts typically appear as white or brown powder and are sold in small plastic or foil packages labeled “not for human consumption.” People who abuse bath salts swallow, inhale, or inject them.

How Do Bath Salts Affect the Brain?

Much is still unknown about the chemicals in bath salts, but they are similar to amphetamines (such as methamphetamine) as well as to MDMA (Ecstasy). So far, research has shown that the most common chemical found in bath salts, methylenedioxypyrovalerone (MDPV), works like cocaine by increasing the brain chemicals dopamine and norepinephrine, causing a feeling of euphoria and hyperactivity. However, MDPV is 10 times more potent than cocaine.

Bath salts may also raise the levels of serotonin, causing hallucinations. Mephedrone and methylone, two other chemicals often sold as bath salts, were found to raise serotonin in a way similar to MDMA.

What Are the Other Health Effects of Bath Salts?

The synthetic chemicals in bath salts are very toxic and have been linked to increases in visits to emergency rooms and poison control centers across the country.

Bath salt abuse can cause the following physical and psychological symptoms:

Racing Heart Panic Attack High blood pressure Dehydration
Chest pains Kidney failure Paranoia Breakdown of skeletal muscle tissue
Hallucinations Insomnia Psychotic and violent behavior Death

What Are We Doing To Prevent Abuse of Bath Salts?

Bath salts users have reported that the drugs trigger intense cravings (or a compulsive urge to use the drug again) and that they are highly addictive.

In response to rising abuse rates of bath salts, President Obama signed into law the Synthetic Drug Abuse Prevention Act, which bans MDPV, mephedrone, and other bath salts ingredients. However, drug manufacturers have responded by developing new versions of bath salts that use ingredients that, while just as toxic, are not yet banned.

If you know someone who is abusing bath salts, tell an adult or contact 1-800-662-HELP to find out how to get help for the person.

Find out more about bath salts.

Tin of bath salts

Alco-Pops: A Refreshment to Rethink

Alcohol companies have tapped into a growing market to introduce underage drinkers to their products, on the basis that kids who acquire a taste for alcoholic drinks early are more likely to get hooked. While it is still illegal for teens to purchase them, “alcopops,” are flavored beer and vodka drinks that contain caffeine, juices, and other flavors. These drinks often sport names like Moonshot, JungleJoose, and Bacardi Breezer Watermelon, to fool you into believing they are harmless flavored drinks.

A photo of a girl that is sick.

But Drinker Beware…

Alcopops may contain 4-7% alcohol or more, higher than the average can of beer containing a little over 3% alcohol content. Alcohol is a depressant, and so can make you tired and slow your brain and reaction time. That affects your ability to make decisions and to act or think properly—it also makes you thirsty, so you keep drinking. Now throw in a strong jolt of caffeine, such as you find in typical energy drinks. While the alcohol in alcopops tends to make you sleepy, the caffeine in them keeps you feeling “up.” Sugar, the major ingredient in many juice drinks and flavorings, also stimulates your brain to give you a short-term energy surge. Now confused from the caffeine, alcohol, and sugar mix, your brain gets tricked in sometimes lethal ways because these drinks don’t taste like alcohol and make you feel less intoxicated than alcohol alone. This leaves you even less aware of how much you’ve consumed and more likely to binge drink.

What’s the Big Deal?

The big deal here is that combining a depressant (alcohol) with stimulants (caffeine and sugar) sends mixed signals to your brain, which can have long-term consequences. So digest the facts before you pop a top: drinking alcohol—including alcopops—can be quite dangerous.

Several glasses of alcohol

Real Teens Ask: What are stimulants?

In a recent Drug Facts Chat Day, freeman-jones of Dr. Henry A. Wise Jr. High School, Maryland asked:

Can taking Ritalin help you if you have not been prescribed Ritalin?

Ritalin is a drug used in the treatment of attention deficit hyperactivity disorder (ADHD) and is classified as a stimulant. The term stimulants can be used to refer to any number of drugs, including prescription drugs like methylphenidate (Ritalin’s scientific name) and dextroamphetamine (Adderall).

People diagnosed (by a doctor) with ADHD can benefit from these drug when they’re used as prescribed. However, teens with an ADHD prescription are sometimes pressured by friends to share some of their pills because they think the pills will help them focus or stay alert or ace an exam.

Trouble is, when you take a pill that’s been prescribed for someone else’s weight, symptoms and body chemistry, or take more than the right dose for your own body, it can bring on more harm than good. Like changing your mood in ways that you can’t control, or raising your blood pressure, heart rate, and body temperature. And when the effects wear off, you might feel extreme fatigue and maybe even depression.

Better than borrowing someone’s prescription pills is GETTING SLEEP. It’s safe and easy and will help you learn and stay mentally and physically alert. Maybe that’s why sleep is such a major part of our lives. Get it for free now (ok, wait ‘til bedtime).

Text - Got Speed?

Word of the Day: Psychoactive Drugs

Have you ever heard the term ”psychoactive drugs?” Drugs in this category act on the central nervous system and and alter its normal, everyday activity, causing changes in mood, awareness, and behavior. Psychoactive drugs disrupt the communication between neurons (brain cells), so abusing them can have serious short- and long-term effects on the brain.

Psychoactive drugs include four groups of drugs: depressants like alcohol and sleeping pills; stimulants like nicotine and ecstasy; opioids like heroin and pain medications; and hallucinogens like LSD.

The term psychoactive drug might make you think of drugs, like LSD, that change your brain and behavior in really extreme ways. LSD is a hallucinogen, or “psychedelic” that significantly alters the brain and the user’s perception of reality. It is also an illicit, or illegal, drug.

But not all psychoactive drugs are illegal. Caffeine is a stimulant found in coffee and energy drinks, and opioids like Vicodin, OxyContin, or morphine are often prescribed by doctors to relieve pain. Abusing prescribed psychoactive drugs is illegal though, and can be as dangerous as abusing cocaine or heroin. That is one reason why they come with warning labels telling people not to drive or operate heavy machinery. Drinking too much caffeine is not good for you either (see chart)!

So legal or illegal, psychoactive drugs demand caution.

NIDA provides lots of information about the different types of psychoactive drugs:

Warning Sign

Girls and Boys Have Different Reasons for Prescription Drug Use

Recent research shows that American teen girls have caught up with boys in their rates of smoking cigarettes and drinking alcohol, which hasn’t always been the case. Here’s something else: teenage girls are now more likely than boys to abuse prescriptions drugs like pain pills and ADHD medications. The thing is—they have different reasons for doing so.

NIDA researchers surveyed hundreds of teens and asked them about their motivations for using particular prescription drugs. For stimulants like ADHD medications, for example, the young men were more likely to abuse them to get high or experiment, while for young women, it was to help them concentrate or stay alert. In other words, the young women were more likely “self-treat” for a specific purpose.

So what’s wrong with that? They’re prescribed by a doctor, after all—how dangerous can they be?

For one thing, when you borrow someone else’s medication or even take your own in a way that wasn’t prescribed, you put yourself at risk for scary side effects that can change your heart rhythm and breathing. And although prescription drugs may seem safer than street drugs, they still can lead to addiction and even death, especially when they’re mixed with other drugs or alcohol.

Do you have a friend who abuses prescription drugs? Do your own survey—ask them why, and let us know what you find out.

image of 2 teens

Alcohol and Drugs Don't Mix

A recent episode of the hit TV show “Glee” focused on the problem of underage drinking. Called “Blame It on the Alcohol,” the episode depicted glee club members narrowly avoiding school suspension for drinking on school grounds—never a smart idea! Not only is it illegal to drink before age 21, but drinking too much alcohol can impair brain function and motor skills and lead to addiction. Mixing alcohol with illicit or other drugs—even legal ones—greatly increases the dangers: Combining alcohol with another central nervous system depressant like Xanax or painkillers like Vicodin can slow your heartbeat and breathing and may lead to death. Mixing alcohol with stimulants like Adderall or club drugs like Ecstasy can cause heart problems, too, as well as strokes and convulsions. Cough and cold medicines that don’t need a prescription can mess you up if you abuse them or combine them with alcohol—once again, heart problems and trouble breathing. Play it safe and don’t mix alcohol with other drugs.

Not LOKO for Alcoholic Energy Drinks

You may remember that a while back, SBB addressed an unhealthy new fad—energy drinks. We speculated that these drinks, although highly publicized in the coolest venues, were not safe even though they promised to deliver an extra dose of energy. Now, SBB confronts an even more dangerous issue: alcoholic energy drinks, like Four LOKO. Why are alcoholic energy drinks so dangerous? They contain two main substances—alcohol and caffeine, the first a depressant and the second a stimulant. These two substances should never be consumed in large quantities and they should definitely never be mixed. Why? Because they have opposite effects on your body that can fool you into drinking more than you can handle. Depressants like alcohol slow down the central nervous system. Drinking a lot of alcohol can affect your coordination and perception and even make you pass out. Stimulants meanwhile “wake up” the central nervous system and increase energy and alertness. Opposites Do Not Attract. The Centers for Disease Control and Prevention says that the caffeine in alcoholic energy drinks masks the effects that the alcohol has on the body, which motivates people to drink more. Worse, the average beer has 4 to 5 percent alcohol, while an alcoholic energy drink is 12 percent alcohol! Therefore, people can get really drunk without realizing it, making them more vulnerable to overdose, alcohol poisoning, and even death. In the past few months, the Food and Drug Administration (FDA) has pulled alcoholic energy drinks like Four LOKO off store shelves, banning them in many states. Better to keep it natural—go for a run or do some yoga to “feel-good.” Loko Drink

Keep "Bath Salts" in the Tub

Bath salts. The name sounds innocent enough, like an old-fashioned cure for tired feet. But these days, “bath salts” are far from what you would find in your local soap aisle at the grocery store or day spa. Bath salts are a new type of drug laced with synthetic stimulants, which people use to get high by swallowing, snorting or injecting them. And…they have just been made illegal.

What Are Bath Salts?

Because these drugs are relatively new and for now unregulated by the U.S. Drug Enforcement Agency (DEA), scientists are not exactly sure of the ingredients in each brand. We do know that the chemicals in these bath salts mimic the effects of amphetamines—stimulants like cocaine or meth—such as racing heart, increased blood pressure and body temperature, and even seizures, which have brought many people to emergency rooms across the country.

According to the head of the Louisiana Poison Center, at least 84 people in that state have been hospitalized after getting high from bath salts. Nationwide, more than 4,000 calls about bath salts have come in to poison centers during the first 7 months of 2011—up from 303 calls in all of 2010.

Risks

It is too early to tell what the exact short- and long-term effects from abusing bath salts is, but what little we do know so far is alarming enough. Effects can include extreme paranoia, hallucinations, and suicidal thoughts, as well as chest pains, soaring blood pressure, and rapid heartbeat. A number of deaths were reported in people who took the drug, including at least one possible suicide.

Several states, including Hawaii, Louisiana, and Michigan, have introduced laws to ban bath salts. The DEA just announced it will make selling or possessing these chemicals illegal for a year while they study them further. SBB will keep you posted on what they learn. If anyone offers you bath salts as a way to get high, let them know not only are they taking big risks, they are also doing something illegal.

Bath Salts