Prescription Opioid Abuse Can Lead to Heroin Abuse
6 Comments You may have heard marijuana referred to as a “gateway drug,” meaning that it can open doors to other kinds of drug abuse. But did you know that prescription painkillers can be gateway drugs to heroin? Some studies show that people who are addicted to heroin often started out abusing prescription painkillers (opioids), like OxyContin or Vicodin.
Not everyone who abuses a prescription opioid will move on to heroin—but why take the risk?
It might begin innocently enough—you think that taking a family member’s prescription painkiller is safer than abusing an illicit drug like Ecstasy, and you start using your dad’s prescription to get high. But what if you can’t stop? Prescription painkillers act on the same brain areas as heroin, after all, and can be very addictive. Once the pills run out, what do you do? If you’re addicted, you may look for another source, and sometimes that means buying heroin, a dangerous move, considering the potential consequences.
NIDA’s Monitoring the Future survey of teen drug use and attitudes shows that high school students have long seen heroin as one of the most dangerous drugs out there. However, once a person is addicted to prescription painkillers and can’t get them anymore, heroin might not sound like such a bad deal.
Both prescription opioids and heroin are extremely hard to stop once a person is addicted. A person trying to quit abusing opioids or heroin usually goes through severe withdrawal, which can cause restlessness, muscle and bone pain, insomnia, diarrhea, vomiting, cold flashes with goosebumps, and involuntary leg movements.
Read more about the dangers of abusing prescription opioids.
Curious what could happen if you abuse someone else’s prescription drugs? “Choose Your Path” with NIDA’s interactive videos. The best part is, if you don’t like your outcome, you can go back and try another path!
Real Teens Ask about Effects of Heroin
At NIDA’s last Chat Day, we got this question from a high school student:
”Why do people scratch a lot when they are high on heroin?”
A NIDA scientist responded that he had done years of research on this topic. He explained: “Heroin activates connections in the brain called opioid receptors. These receptors then activate fibers that transmit itch information (aka ‘pruritus’) to the brain. Thus, heroin users feel itchy. Good question.”
But before heroin can activate opioid receptors, it has to enter the blood stream and reach the brain. So how does this happen?
People usually inject heroin into their blood stream with a syringe. Soon afterwards, the heroin crosses the “blood-brain barrier”—a protective membrane that separates circulating blood from brain fluid in the central nervous system. Once in the brain, heroin is converted to a chemical called morphine and binds rapidly to the opioid receptors already mentioned. These receptors recognize chemicals affecting pain, like morphine.
Heroin users typically report feeling a surge of pleasure, or a “rush,” which makes sense because heroin enters the brain so rapidly. This quality also makes it extremely addictive. Along with the rush usually comes a warm flushing of the skin, dry mouth, and a heavy feeling in the arms and legs, which may be accompanied by nausea, vomiting, and, of course, severe itching. Also, since heroin is a depressant, it clouds your thinking and can slow—or even stop—breathing.
Because heroin is mostly sold on the street, users can’t be sure of the purity (or strength) of the drug they’re taking. Also, because it’s so addictive, they may crave bigger and bigger amounts of the drug to get the same rush they got the first time—which often leads to overdose and death.
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National Institute on Drug Abuse | National Institutes of Health | U.S. Department of Health and Human Services
