NIDA for Teens: The Science Behind Drug Abuse
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Depressants

Alco-Pops: A Refreshment to Rethink

Alcohol companies have tapped into a growing market to introduce underage drinkers to their products, on the basis that kids who acquire a taste for alcoholic drinks early are more likely to get hooked. While it is still illegal for teens to purchase them, “alcopops,” are flavored beer and vodka drinks that contain caffeine, juices, and other flavors. These drinks often sport names like Moonshot, JungleJoose, and Bacardi Breezer Watermelon, to fool you into believing they are harmless flavored drinks.

A photo of a girl that is sick.

But Drinker Beware…

Alcopops may contain 4-7% alcohol or more, higher than the average can of beer containing a little over 3% alcohol content. Alcohol is a depressant, and so can make you tired and slow your brain and reaction time. That affects your ability to make decisions and to act or think properly—it also makes you thirsty, so you keep drinking. Now throw in a strong jolt of caffeine, such as you find in typical energy drinks. While the alcohol in alcopops tends to make you sleepy, the caffeine in them keeps you feeling “up.” Sugar, the major ingredient in many juice drinks and flavorings, also stimulates your brain to give you a short-term energy surge. Now confused from the caffeine, alcohol, and sugar mix, your brain gets tricked in sometimes lethal ways because these drinks don’t taste like alcohol and make you feel less intoxicated than alcohol alone. This leaves you even less aware of how much you’ve consumed and more likely to binge drink.

What’s the Big Deal?

The big deal here is that combining a depressant (alcohol) with stimulants (caffeine and sugar) sends mixed signals to your brain, which can have long-term consequences. So digest the facts before you pop a top: drinking alcohol—including alcopops—can be quite dangerous.

Several glasses of alcohol

Word of the Day: Psychoactive Drugs

Have you ever heard the term ”psychoactive drugs?” Drugs in this category act on the central nervous system and and alter its normal, everyday activity, causing changes in mood, awareness, and behavior. Psychoactive drugs disrupt the communication between neurons (brain cells), so abusing them can have serious short- and long-term effects on the brain.

Psychoactive drugs include four groups of drugs: depressants like alcohol and sleeping pills; stimulants like nicotine and ecstasy; opioids like heroin and pain medications; and hallucinogens like LSD.

The term psychoactive drug might make you think of drugs, like LSD, that change your brain and behavior in really extreme ways. LSD is a hallucinogen, or “psychedelic” that significantly alters the brain and the user’s perception of reality. It is also an illicit, or illegal, drug.

But not all psychoactive drugs are illegal. Caffeine is a stimulant found in coffee and energy drinks, and opioids like Vicodin, OxyContin, or morphine are often prescribed by doctors to relieve pain. Abusing prescribed psychoactive drugs is illegal though, and can be as dangerous as abusing cocaine or heroin. That is one reason why they come with warning labels telling people not to drive or operate heavy machinery. Drinking too much caffeine is not good for you either (see chart)!

So legal or illegal, psychoactive drugs demand caution.

NIDA provides lots of information about the different types of psychoactive drugs:

Warning Sign

Word of the Day: Depressants

What’s the first thing you think of when you hear the word “depressants?” Maybe “depressed” or “sad?” But the drugs called depressants aren’t called that because they’re depressing in the emotional sense.

Depressants slow down (or “depress”) the normal activity that goes on in the brain. Alcohol is a depressant.

Doctors often prescribe central nervous system (CNS) depressants to patients who are anxious or can’t sleep. When used as directed, CNS depressants are safe and helpful for people who need them.

Types of CNS Depressants

CNS depressants can be divided into three main groups:

  • Barbiturates, which are used to treat some forms of epilepsy
  • Benzodiazepines (Valium, Xanax), which can be used to treat severe stress, panic attacks, convulsions, and sleep disorders
  • Sleep medications (Ambien, Sonata, Lunesta), which, as the name suggests, are used to help people with diagnosed sleep problems

How They Work

Most CNS depressants affect the brain in the same way—they enhance the activity of the gamma-aminobutyric acid (GABA). GABA is a neurotransmitter, one of the naturally occurring chemicals in the brain that sends messages between cells. GABA works by slowing down brain activity.

Although different classes of CNS depressants work in unique ways, they ultimately increase GABA activity, which produces a drowsy or calming effect.

Effects When Abused

CNS depressants can be addictive* and should be used only as prescribed. Otherwise, they can bring about major health problems, including addiction. Combining them with alcohol or other drugs like pain medications can lead to slowed breathing and heart rate, and even death.

Find out more about depressants from this NIDA fact sheet (PDF, 718kb).

(*Addiction is when a person compulsively seeks out the drug and cannot control their need for it, even in the face of negative consequences.)

Young man sleeping on homework

Alcohol and Drugs Don't Mix

A recent episode of the hit TV show “Glee” focused on the problem of underage drinking. Called “Blame It on the Alcohol,” the episode depicted glee club members narrowly avoiding school suspension for drinking on school grounds—never a smart idea! Not only is it illegal to drink before age 21, but drinking too much alcohol can impair brain function and motor skills and lead to addiction. Mixing alcohol with illicit or other drugs—even legal ones—greatly increases the dangers: Combining alcohol with another central nervous system depressant like Xanax or painkillers like Vicodin can slow your heartbeat and breathing and may lead to death. Mixing alcohol with stimulants like Adderall or club drugs like Ecstasy can cause heart problems, too, as well as strokes and convulsions. Cough and cold medicines that don’t need a prescription can mess you up if you abuse them or combine them with alcohol—once again, heart problems and trouble breathing. Play it safe and don’t mix alcohol with other drugs.

Real Teens Ask about Effects of Heroin

At NIDA’s last Chat Day, we got this question from a high school student:

”Why do people scratch a lot when they are high on heroin?"

A NIDA scientist responded that he had done years of research on this topic. He explained: “Heroin activates connections in the brain called opioid receptors. These receptors then activate fibers that transmit itch information (aka ‘pruritus’) to the brain. Thus, heroin users feel itchy. Good question.”

But before heroin can activate opioid receptors, it has to enter the blood stream and reach the brain. So how does this happen?

People usually inject heroin into their blood stream with a syringe. Soon afterwards, the heroin crosses the “blood-brain barrier”—a protective membrane that separates circulating blood from brain fluid in the central nervous system. Once in the brain, heroin is converted to a chemical called morphine and binds rapidly to the opioid receptors already mentioned. These receptors recognize chemicals affecting pain, like morphine.

Various drugs names.

Heroin users typically report feeling a surge of pleasure, or a “rush,” which makes sense because heroin enters the brain so rapidly. This quality also makes it extremely addictive. Along with the rush usually comes a warm flushing of the skin, dry mouth, and a heavy feeling in the arms and legs, which may be accompanied by nausea, vomiting, and, of course, severe itching. Also, since heroin is a depressant, it clouds your thinking and can slow—or even stop—breathing.

Because heroin is mostly sold on the street, users can’t be sure of the purity (or strength) of the drug they’re taking. Also, because it’s so addictive, they may crave bigger and bigger amounts of the drug to get the same rush they got the first time—which often leads to overdose and death.

Scratching teen

Not LOKO for Alcoholic Energy Drinks

You may remember that a while back, SBB addressed an unhealthy new fad—energy drinks. We speculated that these drinks, although highly publicized in the coolest venues, were not safe even though they promised to deliver an extra dose of energy. Now, SBB confronts an even more dangerous issue: alcoholic energy drinks, like Four LOKO. Why are alcoholic energy drinks so dangerous? They contain two main substances—alcohol and caffeine, the first a depressant and the second a stimulant. These two substances should never be consumed in large quantities and they should definitely never be mixed. Why? Because they have opposite effects on your body that can fool you into drinking more than you can handle. Depressants like alcohol slow down the central nervous system. Drinking a lot of alcohol can affect your coordination and perception and even make you pass out. Stimulants meanwhile “wake up” the central nervous system and increase energy and alertness. Opposites Do Not Attract. The Centers for Disease Control and Prevention says that the caffeine in alcoholic energy drinks masks the effects that the alcohol has on the body, which motivates people to drink more. Worse, the average beer has 4 to 5 percent alcohol, while an alcoholic energy drink is 12 percent alcohol! Therefore, people can get really drunk without realizing it, making them more vulnerable to overdose, alcohol poisoning, and even death. In the past few months, the Food and Drug Administration (FDA) has pulled alcoholic energy drinks like Four LOKO off store shelves, banning them in many states. Better to keep it natural—go for a run or do some yoga to “feel-good.” Loko Drink

Catching Some ZZZZs: Safe Ways To Get to Sleep

Have you ever had a night when you just couldn’t fall asleep? It’s a terrible feeling. Tossing and turning, watching the minutes click closer to dawn, dreading how tired you’re going to be the next day—the more you try to sleep, the harder it gets. Everyone has trouble sleeping sometimes for many different reasons, like stress and anxiety, or disorders like sleep apnea. Some people are prescribed sleep aids called sedatives, a type of central nervous system depressant, to help them sleep. When used as prescribed—and only by the person they were prescribed for—sedatives are safe and effective for helping people sleep. When abused to get high or even to get sleep, sleep aids can be dangerous, something most teens don’t know. Abusing sleep aids can even be deadly if they are mixed with other substances like alcohol or certain allergy medications because they can slow heart rate and respiration. Six Tips To Help You Sleep If you have consistent trouble getting to sleep, talk to your doctor about it. Meanwhile, here are some things you can do to help you get the 9 hours of sleep you’re supposed to have as a teen.
  • Skip the caffeine. Drink a decaf latte or stick with water. Caffeine is a stimulant and can affect you for up to 24 hours and also cause you to wake often.
  • Keep a routine. Prime your body for sleep—go to bed at the same time each night and wake up at the same time each morning.
  • Exercise, but not before bed. Staying active can help you sleep better, but don’t exercise within 3 hours of going to bed because it can actually wake you up.
  • Block out the light. Cover your windows with heavy curtains or blackout shades. You might even try a sleep mask.
  • Use your bed for sleep. It may be tempting to check Twitter or Facebook before you go to sleep, but it’s best for your brain to associate your bed only with sleep, not socializing, work, or reading. Studies have shown that the computer screen’s bright light can reduce your body’s melatonin levels, which disrupts normal sleep cycles.
  • Try some toast. Carbohydrates like bread, graham crackers, pretzels, and fruit can help make you feel warm and lead you to feel sleepy.
Do you have any ideas that work when you can’t sleep? Tell us in the comments. Tired girl taking sleeping pill